NAIMIT Annual Meeting – 22 – 24 November 2010 – Hannover, Germany
Posted on | November 20, 2010 | No Comments
Program
Monday 22 Nov 2010
12.00- 14.00 Arrival/Welcome – Lunch Buffet
Training Session – Part 1
14.30 – 15.30 Invited Speaker
G Breves (TiHo, Hannover),
Title: Probiotics as immunomodulatory agents and the function of the intestinal tract
15.30 – 15.45 Coffee Break
WP5 – Beta-cell protection and restoration: Dialogue with the immune system – WP leader DL Eizirik
15.45 – 15.50 DL Eizirik (ULB, Brussels) – Overview
15.50 – 16.10 F Moore (ULB, Brussels)
Title: The gene networks regulating STAT-1/IRF-1-induced insulitis
16.10 – 16.25 L Overbergh (KUL, Leuven)
Title: Gene networks modulated by cytokines and vitamin D in mice
16.25 – 16.40 F Dotta (UNISI, Siena)
Title: Islet regeneration
16.40 – 16.55 S Lenzen (MHH, Hannover)
Title: Diabetes prevention in the IDDM rat: Vitamin D and other compounds
16.55 – 17.10 Discussion
17.10 – 17.45 L Overbergh (KUL, Leuven)
Administrative Issues
19.00 Dinner in town
Tuesday, 23 Nov 2010
WP 1 – Re-educating antigen-presenting cells – WP leader B Roep
09.00 – 09.05 Bart Roep – Overview
09.05 – 09.20 T Nicolic (LUMC, Leiden)
Title: Generation of GMP grade DCs and future perspectives
09.20 – 09.35 F Kleijwegt (LUMC, Leiden)
Title: Mechanism of action of human Tregs generated by tolerogenic DCs
09.35 – 09.50 G Bomfim Ferreira (KUL, Leuven)
Title: Proteomic analysis of Vitamin D and Dexamethasone – modified DCs.
09.50 – 10.05 M-B Zocca (DanDrit, Denmark)
Title : SOPs and regulatory issues for clinical translation of DC therapy
10.05 – 10.20 Discussion
WP2 – Restoring the T-cell balance – WP leader M Peakman
10.20 – 10.25 M Peakman (KCL, London) – Overview
10.25 – 10.45 CM Dayan (CU, Cardiff)
Title: Progress on optimizing the tolerogenic potential of the skin for peptide immunotherapy
10.45 – 10.50 P Bingley (UB, Bristol)
Title: Establishing a clinical network for T1D mechanistic and intervention trials
10.50 – 11.00 M Peakman & V Gibson (KCL, London)
Title: Establishing a platform for multi-peptide immunotherapy
11.00 – 11.05 M Peakman (KCL, London)
Title: Phase Ib study of mono-peptide immunotherapy
11.05 – 11.20 Discussion
11.20 – 11.30 Coffee Break
WP3 – TCR-directed immunotherapy – WP leader C. Mathieu
11.30 – 11.35 C Mathieu (KUL, Leuven) – Overview
11.35 – 11.50 R Ashfield (IMC, Abingdon)
Title: Engineering T cell Receptors specific for beta-cell antigens
11.50 – 12.05 C Gysemans (KUL, Leuven)
Title: sTCR specific for beta-cell antigens in treatment of diabetes
12.05 – 12.15 S Megit (IMC, Abingdon)
Title: TCRs for human beta-cell antigens and future perspectives
12.15 – 12.35 J Demengeot (FCG, Lisboa)
Title: In vivo and in vitro suppression assays
12.35 – 12.50 Discussion
12.50 – 13.45 Lunch
13.45 – 14.30 Steering committee
WP 4 – Mucosal intervention for tolerance restoration – WP leader F Dotta
14.30 – 14.35 F Dotta (UNISI, Siena) – Overview
14.35 – 14.50 P Rottiers (AGX, Zwijnaarde/Ghent)
Title: Actobiotics™ in new onset T1D: development of prototypes of L. lactis strains expressing single and multiple beta-cell-specific antigen(s)
14.50 – 15.05 H Korf (KUL, Leuven)
Title: Use of recombinant ActoBiotics in preclinical mouse models
15.05 – 15.20 F Dotta (UNISI, Siena)
Title: L. rhamnosus GG and human iTreg in vitro induction
15.20 – 15.35 Discussion
15.35 – 15.55 Coffee Break
WP6 – Pharmacogenetics: towards individualised therapies – WP leader K Badenhoop
15.55 – 16.00 K Badenhoop (GUF, Frankfurt) – Overview
16.00 – 16.15 K Badenhoop (GUF, Frankfurt)
Title: Vitamin D genetics and peripheral immunity: Pilot study ViDDA1
16.15 – 16.30 E Ramos-Lopez (GUF, Frankfurt)
Title: Vitamin D pathway genes and vitamin D metabolites in T1D
16.30 – 16.45 Todd (UCAM, Cambridge)
Title: Vitamin D and TCR signaling: ongoing studies
16.45– 17.00 Discussion
WP8 – CP management and administration
17.00– 17.30 General Assembly
19.00 Dinner in town
Wednesday, 24 Nov 2010
Training Session – Part 2 – Location: Leibnizhaus Hannover – Room …
09.00 – 09.45 J Todd (UCAM, Cambridge)
Title: Genes and biomarkers in autoimmune diabetes
09.45 – 10.05 T Arndt (MHH, Hannover)
Title: Genetics of the IDDM (LEW.1AR1-iddm) rat model of human type 1 diabetes
10.05 – 10.35 H Korf (KUL, Leuven)
Title: Immune mouse models for type 1 diabetes
10.35 – 11.00 Coffee Break
11.00 – 11.45 S Lenzen (MHH, Hannover)
Title: Rat models of human type 1 diabetes
11.45 – 12.15 Discussion and closing remarks
End of Meeting